Complex biological processes take place every second in the human body and they should be regulated sometimes. The increase of the glucose level in the blood is a case when a medical interventions is required. If the increase of the glucose level in the blood is stopped in time, the development of severe cardiovascular diseases can be prevented. Amaryl is one of the best drugs to prevent and treat pancreatic diabetes.
What is Amaryl?
Amaryl is a classical hypoglycemic drug – derived sulfonylureas of the new third generation. It contains an active ingredient Glimepiride.
The mechanism of the pharmacological action of Amaryl consists in the stimulation of beta-cells of the pancreas which synthesize insulin in reaction to the increase of glucose in the blood.
Pancreatic diabetes type 2 is developed in the setting of the low concentration of insulin, or high resistance of the tissues to the action of insulin. Amaryl not only enhances a secretion of the stimulated insulin but also increases the sensitivity of the tissues (muscle and fatty) to the action of insulin. As a result of these biological processes, a metabolism of glucose is significantly improved and patients can lower the sugar level in the blood.
Amaryl stimulates the increased production of insulin only at the moment of the absorption of glucose by peripheral tissues and during synthesis of glucose in the liver. Then, the insulin level is kept on the low level in order to avoid unwanted side effects.
Indications for the use
- Monotherapy of pancreatic diabetes type 2
- Combined therapy of pancreatic diabetes type 2 with metformin or insulin
In what dose should be Amaryl used?
The dose of Amaryl is detected by the target concentration of glucose in the blood. The medicine should be used in the minimal dose which will be enough to achieve the needed control of the glucose level.
The treatment of the pancreatic diabetes type 2 begins with the minimal daily dose Amaryl 1 mg. In case of the insufficient medical effect, the daily dose can be increased in 2-3 weeks by 1 mg.
The standard daily dose is 4 mg Amaryl for most patients. In rare cases, the dose is increased up to 6-8 mg per day but it is necessary to follow the level of glucose and insulin during the use of these doses. During the combined treatment of the pancreatic diabetes type 2, Amaryl should be used in the minimal dose 1-2 mg per day.
- In case of the acute overdose and prolonged treatment with Amaryl in high doses, severe and dangerous hypoglycemia may develop
- Patients under 16 years old, pregnant women, and also women during lactation are not recommended to take Amaryl
- It is strictly contraindicated to take Amaryl during pancreatic diabetes type 2, renal/hepatic failure, diabetic precoma and coma
- If you have other chronic diseases, consult a doctor before buying Amaryl
Using Amaryl can cause following side effects: nausea, vomiting, symptoms of hypoglycemia, dizziness, and tremor. The symptoms of the side effects of Amaryl pass softly and do not affect the efficiency of the hypoglycemic therapy.
Where to buy Amaryl?
If you do not have a prescription of Amaryl but you need the drug to control the glucose level in the blood, you can order Amaryl in the online pharmacy.
Buying Amaryl online, you can contact a pharmacist of the online pharmacy who will give you recommendations and tell how to correctly take the drug.
You can also read a complete instructions for the use of Amaryl without prescription on the website of the pharmacy. Buying Amaryl online will not take much time. To make the order, 5-7 minutes are needed.