Colospa has an evident spasmolytic action and relaxes smooth muscle fibers in the tissues of the organs of the gastro-intestinal tract. It contains an active ingredient Mebeverine.
Colospa is used during spasms of the gastro-intestinal tract organs (including those which are conditioned by an organic disease), gallstone colic, and intestinal colic, and also during irritable bowel syndrome.
A mechanism of the action of Colospa consists in blocking of sodium ions going to the membrane of the organs of the gastro-intestinal tract, and the muscle fibers are not constricted.
Using the drug, a fast reduction of the spasms occurs by means of the relaxation of the gastro-intestinal muscles, but there is not affection of vermicular movement of the intestine. All processes happen normally, so that a risk of the side effects is minimal.
The active ingredients of Colospa do not reach the blood plasma and do not provide a systemic action to other organs except organs of the gastro-intestinal tract. Mebeverine is completely excreted with urine and bile within a day.
In what dose is Colospa used?
To reduce the spasms of the organs of the gastro-intestinal tract, the pills of Colospa 135 mg are used before eating (20-25 minutes before it) 3 time per day. The pills should be entirely swallowed, without chewing, and with a full glass of water. Besides the common pills of Colospa 135 mg, there are a long-term form of the drug which has 200 mg of the active ingredient Mebeverine.
A long-term form of Colospa 200 mg should be used 2 times per day because a pill acts for 12 hours. After having a stable therapeutic effect, a dose of Colospa is reduced, and the treatment is stopped during a significant improvement.
Children and senior people should not adjust a dose of Colospa, if they do not have restrictions for the use of the drug.
- Colospa is contraindicated during intolerance of fructose, glucose-galactose malabsorption, individual intolerance of Mebeverine
- Children under 12 years old are prescribed Colospa only during the functional disorders of the gastro-intestinal tract which are accompanied by spasms and pain
- There is no medical data about the safety of Colospa during pregnancy. That is why, do not take Colospa during pregnancy and lactation
- Due to the possible development of dizziness, avoid potentially dangerous activities during the use of Colospa
The side effects of Colospa appear in rare cases, and pass in light form. These are usually headache, dizziness, allergic reactions (itching, redness of the skin), diarrhea.
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