Severe depressive disorders may not be treated by the common light antidepressants. To treat the most complicated depressions, doctors recommend to use Elavil, a strong antidepressant which copes with any symptoms of depression and anxiety.
Elavil is a tricyclic antidepressant which contains Amytriptyline. It provides a sedative, anti-anxiety, analgesic effect.
A broad action of Elavil consists in the specific action of Amytriptyline to neurotransmitters in the brain and CNS. It inhibits a reuptake of noradrenaline, serotonin and dopamine at the same time, so that the concentration of these ingredients is increased.
The increase of dopamine and serotonin prevents the development of the depression symptoms and anxious disorder: mood is improved, the sleep is restored, anxiety, fear, and phobia disappear.
The increase of noradrenaline causes a light stimulating effect, so that a light pain-relieving and antihistamine action appears. However, a stimulating effect is rather weak, so that the side effects are hardly probable.
The therapeutic effect of Elavil appears within the first two weeks of the treatment.
Uses and doses
Elavil is effective during the anxious depressive disorders but it can be used for the treatment of the obsessive-compulsory disorders, chronic pain syndrome of the neurogenic origin, psychogenic anorexia, and migraine prevention.
Depending on the type of the psychological disorder, a patient is selected an individual dosage regimen. Elavil is used in the minimal daily dose of 50 mg. The daily dose is taken once, after meals, in the evening.
Depending on severity of the disease symptoms, the dose of Elavil is gradually increased up to 150-200 mg per day. The high daily doses are taken 2-3 times. Every single dose is used after meals, with enough water.
After the disappearance of the expressed signs of the depression or anxiety, the dose of Elavil is lowered up to 100 mg per day, and is taken for the prophylaxis within 6 months. The maximal length of the use of Elavil is 8 months.
Contraindications for the use
- Myocardial infarction
- Acute alcohol/drug intoxication
- Affective insanity
- Severe cardiovascular diseases
- Acute respiratory failure
- Alcohol and drugs which inhibit the functions of the central nervous system can cause hypotension or inhibition of the airway function during the interaction with Elavil. The simultaneous use is contraindicated
- Elavil is incompatible with MAO inhibitors, and therefore the interval between the use of these antidepressants should be at least 14 days
- The simultaneous use of sympathomimetic with Elavil can enhance the load to the functions of the cardiovascular system and cause side effects
The most common side effects which can appear during the use of Elavil are dry mouth, constipation, difficult urination, dizziness, psychosis, tachycardia, hypotension, decreased libido.
The tricyclic antidepressants rather often cause side effects, however, their severity can be regulated with the help of the adjustment of the daily dose of Elavil.
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